Generated by All in One SEO v4.9.10, this is an llms.txt file, used by LLMs to index the site. # Tan Laboratory ## Sitemaps - [XML Sitemap](https://tanlab4generegulation.org/sitemap.xml): Contains all public & indexable URLs for this website. ## Posts - [Title](https://tanlab4generegulation.org/title/) ## Pages - [Welcome to the Tan Laboratory!](https://tanlab4generegulation.org/) - Our lab uses cutting-edge computational and experimental approaches to better understand cellular development and human disease. We are an interdisciplinary team of experimental scientists, computational biologists, and clinician-scientists, and we are jointly affiliated with the Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania. Some of the exciting research - [Publications](https://tanlab4generegulation.org/publications/) - Preprints [5] Pang M, Roy T, Wu X, Tan K. Query-driven generative AI synthesizes multi-modal spatial omics from histology. biorxiv. [4] Diorio C, Shraim R, Thadi, A, Frank-Kamenetskii A, Uppuluri L, Klinghoffer H, Martinez Z, Babu A, Myers RM, Fraietta JA, Hughes A, Sussman J, Xu J, McClory S, Mueller K, Perazelli J, Vella L, - [People](https://tanlab4generegulation.org/people/) - [table id=4 /] Lab Alumni Lab role Current position Joseph Tumulty Postdoc Bioinformatician at Mount Sinai Hospital Wenbao Yu Research assistant professor Assitant professor at Temple University Shovik Bandyopadhyay MSTP student Internal medicine resident at Mass General Brigham Austin Yang Research assistant Master's student at University of Pennsylvania Avi Loren Undergraduate student Master's student at Columbia - [Software](https://tanlab4generegulation.org/software/) - Software can be also be downloaded from GitHub Here. CSI-ANN: Discover functional DNA elements based on their epigenetic profiles miPALM: Infer gene modules from molecular interaction networks CoSBI: Identify combinatorial chromatin modification patterns across genomic loci MAPIT: Identify deregulated molecular pathways by integrating expression, DNA methylation, and protein-protein interaction data SS-CoSBI: Identify combinatorial chromatin modification - [Resources](https://tanlab4generegulation.org/resources/) - Center for Single Cell Biology Cancer Complexity Knowledge Portal Human Tumor Atlas Network (HTAN) Human BioMolecular Atlas Program (HubMAP) Human Cell Atlas - [Research](https://tanlab4generegulation.org/research/) - Gene regulation plays a fundamental role in cellular development and cancer. Our lab uses genomics and systems biology approaches to understand the gene regulatory factors underlying cellular processes. We take snapshots of the regulatory systems using bulk and single-cell omics and imaging assays, and develop computational algorithms to integrate data and generate testable models of - [Positions available](https://tanlab4generegulation.org/positions-available/) - The Tan Lab is often on the lookout for highly motivated experimental or computational graduate students, postdoctoral fellows, or research scientists. To inquire about current opportunities, please contact Dr. Tan directly. - [Contact](https://tanlab4generegulation.org/contact/) - Postal address: The Children's Hospital of Philadelphia 4002 Colket Translational Research Building (CTRB) 3501 Civic Center Boulevard Philadelphia, PA 19104 USA Tel: Office: 267-425-0050 Computer lab: 267-425-0053 Wet lab: 267-425-0058 ## Feeds - [My Feed](https://tanlab4generegulation.org/fts/my-feed/)